UKBB FALLS GWAS Data Release 2020

UKBB FALLS GWAS Data Release 2020

The GEnetic Factors for OSteoporosis (GEFOS) Consortium is a large international collaboration comprising numerous research groups. Osteoporosis is a common age-related complex disease with a strong genetic component. The UK Biobank is a health resource from the United Kingdom that has genetic data and phenotype measurements in 500,000 individuals, representative of the general population. We analyzed the full batch of genetic data, including genotyping and imputed data in up to 451,179 participants. We performed genome-wide association studies fall history.

Release

This release comprises the summary data from our 2020 GWAS on falls in the full batch of genetic data from the UK Biobank. Analyses were performed based on the HRC imputation panel (hg19) including ~7,500,000 SNPs with MAF ≥ 1% and acceptable imputation quality (info score > 0.3).

Data file description

Each file contains the following information: rsID for each variant Chromosome Position (hg19) Effect allele Non-effect allele Effect allele frequency Imputation quality score Effect estimate (logOR) Standard error of the effect estimate (logOR.SE) P-value

Publications

Terms of Use

We require appropriate attribution for use of data in a product, service, or publication by citing the article generating this set of results (Trajanoska et al, Biology Communication 2020) and acknowledging its use.

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By downloading the files below, you explicitly agree to the Terms of Use stipulated above.